Scientists Develop New Way to Target Alzheimer’s

Scientists are aiming for a new way to battle Alzheimer’s – by targeting toxic particles that trigger the brain disease. Do you think this will be a success?

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It’s a great day for science as they continue to try to find a cure of Alzheimer’s Disease. While scientists all over the world try and understand the disease and find cures for it, one research is being hailed as a world first, as they aim to target toxic particles that trigger the brain disease, according to a new report by the New York Post.

Alzheimer’s disease is an irreversible progressive brain disorder that slowly destroys memory and thinking skills, and eventually the ability to carry out the simplest tasks. Alzheimer’s disease is currently ranked as the sixth leading cause of death in the United States, but recent estimates indicate that the disorder may actually rank third, right behind heart disease and cancer, according to the U.S. Department of Health & Human Services.

Alzheimer’s symptoms usually first appear in people 65 or older, but symptoms can appear in people younger than that, which is referred to as early-onset Alzheimer’s. Five percent of people who have Alzheimer’s disease, will develop symptoms before they are 65, according to the Mayo Clinic.

Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities, according to the U.S. Department of Health & Human Services.

There is no current cure for Alzheimer’s, as scientists continue to unravel the complex brain changes involved in the onset and the progression of the disease. Aging progresses the disease, but it seems highly likely that damage to the brain starts a decade before memory and other cognitive problems appear. This stage is known as the preclinical stage of Alzheimer’s disease, where people seem to be symptom-free, but toxic changes are taking place in the brain.

Experts at Cambridge University and from Sweden have identified these particles as the prime cause of Alzheimer’s and worked out a formula for targeting them, the report states. The findings were published in the Proceedings of the National Academy of Sciences, Cambridge researcher Michele Vendruscolo says: “We’ve devised the first strategy to go after the cause.”

Vendruscolo added, “the hope is that new drugs can be developed.”

A healthy brain has a quality control system that gets rid of any excessive amount of these proteins, while in Alzheimer’s, proteins called oligomers that usually help brain cells to function normally “go rogue,” by forming clumps that kill healthy nerve cells, the report states. “Over time, the brain begins to shrink, causing memory failure and personality changes.”

Prior to this new study, no one has been successful at developing a way to go after the cause, although many have tried, but failed. Most drugs on the market, help slow it down or help tackle the symptoms associated with the disease.

A separate study, by the University Hospital of Tubingen in Germany, has shown that two and a half hours a week of exercise can delay the effects of Alzheimer’s. The brain scores of people who did physical activity like swimming and running for 150 minutes a week were better, according to the New York Post.

While most of us don’t know if we will get Alzheimer’s Disease later in life, others do because it can be genetic. Some with early-onset Alzheimer’s have a type of disease called “familial Alzheimer’s disease,” which means they most likely have inherited it from a parent or grandparent who have developed Alzheimer’s at a younger age.

Genetic testing for mutations that show links of the disease can be run, something you may want to do if you know your biological mother or father carries a genetic mutation for early-onset FAD.

Late-onset Alzheimer’s, which is what most people have, has yet to be completely understood. Some causes point to a combination of genetic, environmental, and lifestyle factors that affect a person’s risk of developing the disease.

A nutritious diet, physical activity, social engagement, and mentally stimulating pursuits have all been associated with helping people stay healthy as they age, which might help reduce the risks of cognitive decline and Alzheimer’s disease, according to the U.S. Department of Health and Human Services.

The new study will be a new way to battle Alzheimer’s and their work may lead to tests on new drug treatments by 2020. For a disease so complex, we only hope this is the beginning of success for the disease, or at least on the right path to preventing and curing Alzheimer’s Disease. Read the full story from the New York Post here.


Here’s how people on the Zip app are weighing in on this all over the country!

Scientists are aiming for a new way to battle Alzheimer’s – by targeting toxic particles that trigger the brain disease. Do you think this will be a success?

Totals
88% Cure is coming
12% Too complex
Males
89% Cure is coming
11% Too complex
Females
87% Cure is coming
13% Too complex

Cure is coming

Too complex

Scientists Develop New Way to Target Alzheimer’s


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